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Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
Alexander Chinarev

EDUCATION AND SCIENTIFIC CARRIER

1990-1996

M. V. Lomonosov Moscow State Academy of fine chemical technology (MITHT), Faculty of biotechnology and organic synthesis, Department of polymer synthesis, specialization in synthesis and technology of polymers for medicine, biology and biotechnology.

B.S. Thesis: "Preparation of monodisperse polystyrene microspheres by emulsion polymerization", 1994, (Prof. Dr. I. A. Gritskova).

M.S. Thesis: "Synthesis of symmetrically branched oligovalent and polymer conjugates of N-acetylneuraminic acid", 1996, (Prof. Dr. V. P. Zubov, Dr. A. B. Tuzikov).

1996-1999

Post-graduated in Shemyakin&Ovchinnikov Institute of Bioorganic Chemistry RAS, specialization in bioorganic chemistry.

PhD Thesis: "Synthesis of tetravalent and multivalent self-associated blockers of influenza virus", (Prof. Dr. N. V. Bovin).

 

1999 - present time

Research scientist, Laboratory of carbohydrate chemistry, Shemyakin&Ovchinnikov Institute of Bioorganic Chemistry, RAS.

 

CURRENT RESEARCH INTERESTS

Design and synthesis of carbohydrate multimerics, oligosaccharide synthesis; polymer synthesis; carbohydrate-protein interaction; carbohydrate-mediated pathogen to cell adhesion; immune response to carbohydrates; supramolecular chemistry, biomedical nanotechnology.

 

CURRICULUM VITAE, PDF file

 

 



Position: researcher
Phone: +7 495 330 0300; Fax: +7 495 330 5592
E.mail:  Send mail


Publications: (total 30) [print version]

1. O.E.Galanina, A.A.Chinarev, N.V.Shilova, M.A.Sablina, N.V.Bovin
Immobilization of polyacrylamide-based glycoconjugates on solid phase in immunosorbent assays.
Methods Mol. Biol., 808, pp.167-182, (2012) [abstract] [PMID: 22057525]

2. S.V.Tsygankova, A.A.Chinarev, A.B.Tuzikov, I.S.Zaitsev, N.Severin, A.A.Kalachev, J.P.Rabe, N.V.Bovin
Assembly of oligoglicine layers on mica surface.
Biomater. Nanobiotechnol., 2, pp.90-96, (2011) [abstract] [full PDF]

3. N.Y.Kulikova, A.M.Shpirt, A.A.Chinarev, L.O.Kononov
Synthesis of O-Acetylated N-Acetylneuraminic Acid Glycal.
In Carbohydrate Chemistry Proven Methods Vol. 1., Kovac, P., (ed.) CRC PressTaylor Francis, Boca Raton, FL, pp.245-250, (2011) [abstract]

4. A.A.Chinarev, A.B.Tuzikov, A.I.Zinin, N.V.Bovin
Substituted Benzyl Glycosides of N-Acetylneuraminic Acid
In Carbohydrate Chemistry Proven Methods Vol. 1., Kovac, P., (ed.) CRC PressTaylor Francis, Boca Raton, FL, pp.251-258, (2011) [abstract]

5. T.V.Pochechueva, A.A.Chinarev, M.Spengler, E.Yu.Korchagina, V.Heinzelmann-Schwarz, N.V.Bovin, R.Rieben
Multiplex suspension array for human anti-carbohydrate antibody profiling.
Analyst, 136(3), pp.560-569, (2011) [abstract] [full PDF] [PMID: 21107457]

6. V.V.Prokhorov, D.V.Klinov, A.A.Chinarev, A.B.Tuzikov, I.V.Gorokhova, N.V.Bovin
High-resolution atomic force microscopy study of hexaglycylamide epitaxial structures on graphite.
Langmuir, 27, pp.5879-5880, (2011) [abstract] [full PDF] [PMID: 21351798]

7. T.V.Pochechueva, F.Jacob, D.R.Goldstein, M.E.Huflejt, A.A.Chinarev, R.Caduff, D.Fink, N.V.Bovin, etc.
Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies.
Glycoconjugate Journal, 28, pp.507-517, (2011) [abstract] [full PDF] [PMID: 21948103]

8. A.A.Chinarev, O.E.Galanina, N.V.Bovin
Biotinylated Multivalent Glycoconjugates for Surface Coating.
Methods Mol. Biol., 600, pp.67-78, (2010) [abstract] [full PDF] [PMID: 19882121]

9. L.V.Mochalova, R.Bright, X.Xu, E.Yu.Korchagina, A.A.Chinarev, N.V.Bovin, A.Klimov
Shift in oligosaccharide specificities of hemagglutinin and neuraminidase of influenza B viruses resistant to neuraminidase inhibitors.
Glycoconjugate Journal, 27, pp.321-327, (2010) [abstract] [full PDF] [PMID: 20195900]

10. O.A.Gus'kova, P.G.Khalatur, A.R.Khokhlov, A.A.Chinarev, S.V.Tsygankova, R.Bright
Oligoglycine surface structures: molecular dynamics simulation. [Article in Russian]
Russ. J. Bioorgan. Chem., 36(5), pp.574-580, (2010) [abstract] [full PDF] [PMID: 21063448]

11. P.A.Chugunov, A.A.Chinarev, A.B.Tuzikov, A.A.Formanovsky, A.S.Gambaryan, N.V.Bovin
Monosialoside with multimer-like anti-influenza potency.
Mendeleev Communs., 19(2), pp.62-63, (2009) [abstract] [full PDF]

12. A.Alikhani, E.Yu.Korchagina, A.A.Chinarev, N.V.Bovin, W.J.Federspiel
High molecular weight blood group A trisaccharide-polyacrylamide glycoconjugates as synthetic blood group A antigens for anti-A antibody removal devices.
J. Biomed. Mater. Res. B. Appl. Biomater., 91(2), pp.845-854, (2009) [abstract] [full PDF] [PMID: 19582848]

13. O.E.Selina, A.A.Chinarev, P.Obukhova, A.Bartkowiak, N.V.Bovin, E.A.Markvicheva
Alginate-chitosan microspheres for the specific sorption of antibodies. [Article in Russian]
Russ. J. Bioorgan. Chem., 34(5), pp.522-529, (2008) [abstract] [full PDF] [PMID: 18695725]

14. N.V.Bovin, A.B.Tuzikov, A.A.Chinarev
Oligoglycines: Materials with unlimited potential for nanotechnologies.
Nanotechnologies in Russia, 3(5-6), pp.48-61, (2008) [abstract] [full PDF]

15. I.V.Gorokhova, A.A.Chinarev, A.B.Tuzikov, S.V.Tsygankova, N.V.Bovin
Spontaneous and promoted association of linear oligoglycines. [Article in Russian]
Russ. J. Bioorgan. Chem., 32(5), pp.467-476, (2006) [abstract] [full PDF] [PMID: 17042264]

16. N.V.Shilova, O.E.Galanina, T.V.Pochechueva, A.A.Chinarev, V.A.Kadykov, A.B.Tuzikov, N.V.Bovin
High molecular weight neoglycoconjugates for solid phase assays.
Glycoconjugate Journal, 22(1-2), pp.43-51, (2005) [abstract] [full PDF] [PMID: 15864434]

17. A.S.Gambaryan, S.S.Yamnikova, D.K.Lvov, A.B.Tuzikov, A.A.Chinarev, G.V.Pazynina, R.G.Webster, M.N.Matrosovich, etc.
Receptor specificity of influenza viruses from birds and mammals: New data on involvement of the inner fragments of the carbohydrate chain
Virology, 334(2), pp.276-283, (2005) [abstract] [full PDF] [PMID: 15780877]

18. A.S.Gambaryan, A.I.Karasin, A.B.Tuzikov, A.A.Chinarev, G.V.Pazynina, N.V.Bovin, M.N.Matrosovich, C.W.Olsen, etc.
Receptor-binding properties of swine influenza viruses isolated and propagated in MDCK cells
Virus Res., 114(1-2), pp.15-22, (2005) [abstract] [full PDF] [PMID: 15996787]

19. A.S.Gambaryan, E.Y.Boravleva, M.N.Matrosovich, H.-d.Klenk, E.V.Moiseeva, A.B.Tuzikov, A.A.Chinarev, G.V.Pazynina, etc.
Polymer-bound 6'sialyl-N-acetyllactosamine protects mice infected by influenza virus
Antiviral Research, 68(3), pp.116-123, (2005) [abstract] [full PDF] [PMID: 16214231]

20. N.V.Bovin, A.B.Tuzikov, A.A.Chinarev, A.S.Gambaryan
New approaches to antiviral therapy.
Molecular Medicine (Rus.), 3, pp.56-61, (2004)

21. D.Katinger, L.V.Mochalova, A.A.Chinarev, N.V.Bovin, J.Romanova
Specificity of neuraminidase activity from influenza viruses isolated in different hosts tested with novel substrates.
Arch. Virol., 149(11), pp.2131-2140, (2004) [abstract] [full PDF] [PMID: 15503202]

22. N.V.Bovin, A.B.Tuzikov, A.A.Chinarev, A.S.Gambaryan
Multimeric glycotherapeutics: new paradigm.
Glycoconjugate Journal, 21(8-9), pp.471-478, (2004) [abstract] [full PDF] [PMID: 15750788]

23. L.V.Mochalova, A.S.Gambaryan, J.Romanova, A.B.Tuzikov, A.A.Chinarev, D.Katinger, H.Katinger, N.V.Bovin, etc.
Receptor-binding properties of modem human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggs.
Virology, 313(2), pp.473-480, (2003) [abstract] [full PDF] [PMID: 12954214]

24. A.B.Tuzikov, A.A.Chinarev, A.S.Gambaryan, V.A.Oleinikov, D.V.Klinov, N.B.Matsko, S.V.Khaidukov, N.V.Bovin, etc.
Polyglycine II nanosheets: Supramolecular antivirals?
ChemBioChem, 4(2-3), pp.147-154, (2003) [abstract] [full PDF] [PMID: 12616627]

25. G.V.Pazynina, M.A.Sablina, A.B.Tuzikov, A.A.Chinarev, N.V.Bovin
Synthesis of complex α2-3 sialooligosaccharides, including sulfated and fucosylated ones, using Neu5Acα2-3Gal as a building block.
Mendeleev Communs., 13, pp.245-248, (2003) [abstract] [full PDF]

26. G.V.Pazynina, A.B.Tuzikov, A.A.Chinarev, P.Obukhova, N.V.Bovin
Simple stereoselective synthesis of α2-6 sialooligosaccharides.
Tetrahedron Letters, 43, pp.8011-8013, (2002) [abstract] [full PDF]

27. A.S.Gambaryan, A.B.Tuzikov, A.A.Chinarev, L.R.Juneja, N.V.Bovin, M.N.Matrosovich
Polymeric inhibitor of influenza virus attachment protects mice from experimental influenza infection.
Antiviral Research, 55(1), pp.201-205, (2002) [abstract] [full PDF] [PMID: 12076764]

28. D.E.Tsvetkov, P.E.Cheshev, A.B.Tuzikov, A.A.Chinarev, G.V.Pazynina, M.A.Sablina, A.S.Gambaryan, N.V.Bovin, etc.
Neoglycoconjugates Based on Dendrimer Poly(aminoamides). [Article in Russian]
Russ. J. Bioorgan. Chem., 28(6), pp.518-534, (2002) [abstract] [full PDF] [PMID: 12528464]

29. M.A.Dikusar, I.V.Kubrakova, A.A.Chinarev, N.V.Bovin
Polymerization of 4-nitrophenylacrylate under microwave heating conditions. [Article in Russian]
Russ. J. Bioorgan. Chem., 27(6), pp.457-461, (2001) [abstract] [full PDF] [PMID: 11811070]

30. A.A.Chinarev, A.B.Tuzikov, A.S.Gambaryan, M.N.Matrosovich, A.Imberty, N.V.Bovin
Tetravalent blockers for influenza virus hemagglutinin
In: Sialobiology and Other Novel Forms of Glycosylation, Inoue, Inoue, Troy, Eds., Gakushin Publishing Co, Osaka, pp.135-143, (1999) [abstract]

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