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Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
Elena Korchagina , Ph.D.

AffilIation and official address:
Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10,
Moscow 117997, Russia

Date of birth: January 02, 1961

Family status: single

Nationality: Russian

 

EDUCATION

·         Moscow State University, Department of Chemistry, 1978-1983,
M.Sc.Thesis "Study of chiral-optical properties of series γ-piperidones", Supervisor Dr. G.V. Grishina, Laboratory of Organic Synthesis.

·         Ph.D.Thesis "Blood group antigens A and B, their fragments and analogs: synthesis, immunochemical properties, application in haematology", 1991, Institute of Bioorganic Chemistry, Laboratory of Carbohydrates Chemistry (Dr. N.V.Bovin).

 

CARRIER/EMPLOYMENT

·         Research scientist, Shemyakin Institute, Moscow – 1983 -1985,

·         Dr. (candidate, equivalent to Ph.D.) - 1991, Shemyakin Institute, Moscow

·         Research scientist, Institute of Biotechnology, Moscow – 1985 –1988

·         Research scientist, Shemyakin Institute, Moscow – 1988-1998

·         Senior research scientist, Shemyakin Institute, Moscow – 1998- present time,

 

JOB OBJECTIVE: chemistry, biochemistry, immunochemistry of glycoconjugates; carbohydrate-protein interaction and carbohydrate-carbohydrate interaction; antibodies to carbohydrates; histo blood group antigens;

 

QUALIFICATIONS: experience in synthesis of oligosaccharides, neoglycoconjugates, glycolipids, glycosorbents; study of specificity anti-carbohydrate antibodies;

 

CURRENT RESEARCH INTERESTS: synthesis of oligosaccharides and neoglycoconjugates; carbohydrate-protein and carbohydrate-carbohydrate interaction; xenotransplantation, transplantation, oncodiagnostics.



Position: senior scientist
Phone: +7 495 330-03-00; Fax: +7 495 330-55-92
E.mail:  Send mail


Publications: (total 58, shown from 1 to 30) [print version]

1. I.M.Ryzhov, E.Yu.Korchagina, I.S.Popova, N.V.Bovin
Block synthesis of A tetrasaccharides (types 1, 3, and 4) related to the human ABO blood group system.
Carbohydrate Research, 351, pp.17-25, (2012) [abstract] [PMID: 22305408]

2. Y.Banz, O.M.Hess, E.Yu.Korchagina, E.A.Gordeeva, S.C.Robson, E.Csizmadia, D.Mettler, N.V.Bovin, etc.
Evaluation of multimeric tyrosine-O-sulfate as a cytoprotectant in an in vivo model of acute myocardial infarction in pigs.
Cardiology, 121, pp.59-70, (2012) [abstract] [full PDF] [PMID: 22398380]

3. E.Yu.Korchagina, A.B.Tuzikov, A.A.Formanovsky, I.S.Popova, S.Henry, N.V.Bovin
Toward creating cell membrane glyco-landscapes with glycan lipid constructs.
Carbohydrate Research, 356, pp.238-246, (2012) [abstract] [full PDF] [PMID: 22551471]

4. O.A.Vokhmyanina, E.M.Rapoport, S.André, V.V.Severov, I.M.Ryzhov, G.V.Pazynina, E.Yu.Korchagina, N.V.Bovin, etc.
Comparative study of the glycan specificities of cell-bound human tandem-repeat-type galectin-4, -8 and -9.
Glycobiology, 22(1), pp.207-217, (2012) [abstract] [full PDF] [PMID: 22547138]

5. T.V.Pochechueva, A.A.Chinarev, M.Spengler, E.Yu.Korchagina, V.Heinzelmann-Schwarz, N.V.Bovin, R.Rieben
Multiplex suspension array for human anti-carbohydrate antibody profiling.
Analyst, 136(3), pp.560-569, (2011) [abstract] [full PDF] [PMID: 21107457]

6. E.M.Hadac, M.J.Federspiel, E.Cherny, A.B.Tuzikov, E.Yu.Korchagina, N.V.Bovin, S.Russell, S.Henry
Fluorescein and radiolabeled Function-Spacer-Lipid constructs allow for simple in vitro and in vivo bioimaging of enveloped virions
J. Virol. Methods, 176(1-2), pp.78-84, (2011) [abstract] [PMID: 21703308]

7. P.Obukhova, E.Yu.Korchagina, S.Henry, N.V.Bovin
Natural anti-A and anti-B of the ABO system: allo- and autoantibodies have different epitope specificity.
Transfusion, 52(4), pp.860-869, (2011) [abstract] [PMID: 21981750]

8. O.A.Vokhmyanina, E.M.Rapoport, I.M.Ryzhov, E.Yu.Korchagina, G.V.Pazynina, V.V.Severov, H.-J.Gabius, N.V.Bovin, etc.
Carbohydrate specificity of chicken and human tandem-repeat-type galectins-8 in composition of cells.
Biochemistry (Moscow), 76(10), pp.1185-1192, (2011) [abstract]

9. O.V.Kurmyshkina, E.M.Rapoport, E.V.Moiseeva, E.Yu.Korchagina, T.V.Ovchinnikova, G.V.Pazynina, I.M.Belyanchikov, N.V.Bovin
Glycoprobes as a tool for the study of lectins expressed on tumor cells.
Acta Histochem., 112(2), pp.118-126, (2010) [abstract] [PMID: 19285339]

10. O.V.Kurmyshkina, E.M.Rapoport, E.V.Moiseeva, E.Yu.Korchagina, T.V.Ovchinnikova, G.V.Pazynina, I.M.Belyanchikov, N.V.Bovin
Glycoprobes as a tool for the study of lectins expressed on tumor cells.
Acta Histochem., 112, pp.118-126, (2010) [abstract] [PMID: 19285339]

11. L.V.Mochalova, R.Bright, X.Xu, E.Yu.Korchagina, A.A.Chinarev, N.V.Bovin, A.Klimov
Shift in oligosaccharide specificities of hemagglutinin and neuraminidase of influenza B viruses resistant to neuraminidase inhibitors.
Glycoconjugate Journal, 27, pp.321-327, (2010) [abstract] [full PDF] [PMID: 20195900]

12. S.Gautman, E.Yu.Korchagina, N.V.Bovin, W.J.Federspiel
Specific antibody filter (SAF) binding capacity enhancement to remove anti-A antibodies.
J. Biomed. Mater. Res. B. Appl. Biomater., 95(2), pp.475-480, (2010) [abstract] [PMID: 20878917]

13. E.Yu.Korchagina, I.M.Ryzhov, K.A.Byrgazov, I.S.Popova, S.N.Pokrovsky, N.V.Bovin
Block synthesis of blood group tetrasaccharides B (types 1, 3 and 4).
Mendeleev Communs., 19(3), pp.152-154, (2009) [abstract] [full PDF]

14. A.Alikhani, E.Yu.Korchagina, A.A.Chinarev, N.V.Bovin, W.J.Federspiel
High molecular weight blood group A trisaccharide-polyacrylamide glycoconjugates as synthetic blood group A antigens for anti-A antibody removal devices.
J. Biomed. Mater. Res. B. Appl. Biomater., 91(2), pp.845-854, (2009) [abstract] [full PDF] [PMID: 19582848]

15. S.Gautman, E.Yu.Korchagina, N.V.Bovin, W.J.Federspiel
Monoclonal anti-A antibody removal by synthetic A antigen immobilized on specific antibody filters.
Biotechnol. Bioeng., 99(4), pp.876-883, (2008) [abstract] [PMID: 17705231]

16. T.Frame, T.Carroll, E.Yu.Korchagina, N.V.Bovin, S.Henry
Synthetic glycolipid modification of red blood cell membranes
Transfusion, 47(5), pp.876-882, (2007) [full PDF] [PMID: 17465953]

17. E.I.Kovalenko, E.Abakushina, W.Telford, V.Kapoor, E.Yu.Korchagina, S.V.Khaidukov, I.M.Molotkovskaya, N.V.Bovin, etc.
Clustered carbohydrates as a target for natural killer cells: a model system.
Histochem Cell Biol., 127(3), pp.313-326, (2007) [abstract] [PMID: 17226049]

18. L.V.Mochalova, V.S.Kurova, J.A.Shtyria, E.Yu.Korchagina, A.S.Gambaryan, I.M.Belyanchikov, N.V.Bovin
Oligosaccharide specificity of influenza H1N1 virus neuraminidases.
Arch. Virol., 152(11), pp.2047-2057, (2007) [abstract] [PMID: 17680329]

19. M.Sundbck, P.Grufman, J.Teller, F.Westphal, E.Yu.Korchagina, N.V.Bovin, J.Holgersson
Quantification of blood group A and B antibodies by flow cytometry using beads carrying A or B trisaccharides.
Transplantation, 84(12), (2007) [abstract] [PMID: 18162983]

20. J.C.Solovan, H.I.Oh, A.Alikhani, S.Gautman, K.Vlasova, E.Yu.Korchagina, N.V.Bovin, W.J.Federspiel
Synthetic blood group antigens for anti-A removal device and their interaction with monoclonal anti-A IgM.
Transpl Immunol, 16(3-4), pp.245-249, (2006) [abstract] [PMID: 17138061]

21. L.V.Mochalova, E.Yu.Korchagina, V.S.Kurova, J.A.Shtyria, A.S.Gambaryan, N.V.Bovin
Fluorescent assay for studying the substrate specificity of neuraminidase
Analytical Biochemistry, 341(1), pp.190-193, (2005) [full PDF] [PMID: 15866544]

22. M.Duk, G.Kuznierz-Alejska, E.Yu.Korchagina, N.V.Bovin, S.Bochenek, E.Lisowska
Anti-α-galactosyl antibodies recognizing epitopes terminating with α1,4-linked galactose: human “natural” and mouse monoclonal anti-NOR and anti-P1 antibodies.
Glycobiology, 15(2), pp.109-118, (2005) [abstract] [PMID: 15342552]

23. E.Yu.Korchagina, T.V.Pochechueva, P.Obukhova, A.A.Formanovsky, A.Imberty, R.Rieben, N.V.Bovin
Design of the blood group AB glycotope
Glycoconjugate Journal, 22(3), pp.127-133, (2005) [abstract] [full PDF] [PMID: 16133833]

24. Y.Banz, O.M.Hess, S.C.Robson, D.Mettler, A.Haeberli, E.Csizmadia, E.Yu.Korchagina, N.V.Bovin, etc.
Locally targeted cytoprotection with dextran sulfate attenuates experimental porcine myocardial ischaemia/reperfusion injury
Eur Heart J., 26(21), pp.2334-2343, (2005) [abstract] [full PDF] [PMID: 16055495]

25. Y.Banz, T.Cung, E.Yu.Korchagina, N.V.Bovin, A.Herbeli, R.Rieben, etc.
Endothelial cell protection and complement inhibition in xenotransplantation: a novel in vitro model using whole blood
Antiviral Research, 12(6), pp.434-443, (2005) [abstract] [PMID: 16202066]

26. T.Laumonier, A.J.Walpen, K.M.Matozan, E.Yu.Korchagina, N.V.Bovin, A.Haeberli, P.J.Mohacsi, R.Rieben
Multimetric tyrosine sulfate acts as an endothelial cell protectant and prevents complement activation in xenotransplantation models.
Xenotransplantation, 11(3), pp.262-268, (2004) [abstract] [full PDF] [PMID: 15099206]

27. T.Laumonier, P.J.Mohacsi, K.M.Matozan, Y.Banz, A.Haeberli, E.Yu.Korchagina, N.V.Bovin, B.Vanhove, etc.
Endothelial cell protection by dextran sulfate: a novel strategy to prevent acute vascular rejection in xenotransplantation.
Amer. J. Transpl., 4(2), pp.181-187, (2004) [abstract] [PMID: 14974938]

28. T.Laumonier, A.J.Walpen, C.F.Maurus, P.J.Mohacsi, K.M.Matozan, E.Yu.Korchagina, N.V.Bovin, R.Rieben, etc.
Dextran sulfate acts as an endothelial cell protectant and inhibits human complement and natural killer cell-mediated cytotoxicity against porcine cells.
Transplantation, 76(5), pp.838-843, (2003) [abstract] [full PDF] [PMID: 14501864]

29. H.-C.Siebert, S.André, S.-Y.Lu, M.Frank, H.Kaltner, J.A.van Kuik, E.Yu.Korchagina, N.V.Bovin, etc.
Unique conformer selection of the human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins.
Biochemistry, 42(50), pp.14762-14773, (2003) [abstract] [PMID: 14674750]

30. T.V.Pochechueva, E.V.Shipova, G.V.Pazynina, E.Yu.Korchagina, N.V.Bovin
ELISA-based mapping of anti-A, anti-B and anti-AB mAbs with synthetic oligosaccharides and glycoconjugates.
4th Workshop on Monoclonal Antibodies Against Human Red Blood Cells and Related Antigens, p.7, (2001)

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